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Laura H Heitman Selected Research

CCR2 Receptors

3/2022Targeting the CCL2-CCR2 axis for atheroprotection.
1/2022Targeting the CCL2-CCR2 axis for atheroprotection.
11/2021Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2.
1/2017A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy.
3/2015When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonists.

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Laura H Heitman Research Topics

Disease

11Neoplasms (Cancer)
06/2022 - 04/2009
6Atherosclerosis
03/2022 - 03/2015
4Inflammation (Inflammations)
03/2022 - 10/2014
4Multiple Sclerosis
12/2016 - 10/2013
3Infections
03/2022 - 01/2021
3Rheumatoid Arthritis
02/2022 - 10/2013
3Neoplasm Metastasis (Metastasis)
01/2022 - 08/2020
3Neuralgia (Stump Neuralgia)
12/2016 - 10/2013
2Cardiovascular Diseases (Cardiovascular Disease)
03/2022 - 01/2022
2Atherosclerotic Plaque (Atheroma)
03/2022 - 01/2022
2Asthma (Bronchial Asthma)
01/2022 - 12/2016
2Mental Disorders (Mental Disorder)
10/2021 - 12/2016
2Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2020 - 01/2014
2Cardiac Arrhythmias (Arrythmia)
01/2020 - 10/2019
2Insulin Resistance
01/2019 - 03/2015
1Nervous System Diseases (Neurological Disorders)
01/2022
1Chronic Obstructive Pulmonary Disease (COPD)
01/2022
1Heart Failure
10/2020
1Long QT Syndrome
01/2020
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2020
1Stroke (Strokes)
01/2020
1Atrioventricular Block
10/2019
1Torsades de Pointes (Torsade de Pointes)
10/2019
1Type 2 Diabetes Mellitus (MODY)
01/2019
1Arthritis (Polyarthritis)
01/2019
1Neuroinflammatory Diseases
02/2018
1Neuroblastoma
01/2018
1Pathologic Processes
12/2017
1Diabetic Nephropathies (Diabetic Nephropathy)
12/2016
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2016
1Tachycardia (Tachyarrhythmias)
04/2016
1Cardiotoxicity
08/2015
1Autoimmune Diseases (Autoimmune Disease)
02/2015
1Communicable Diseases (Infectious Diseases)
06/2014

Drug/Important Bio-Agent (IBA)

10Pharmaceutical PreparationsIBA
03/2022 - 12/2016
7LigandsIBA
03/2022 - 10/2013
5CCR2 ReceptorsIBA
03/2022 - 03/2015
5ChemokinesIBA
03/2022 - 10/2013
3Adenosine A1 ReceptorIBA
06/2022 - 10/2020
3G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2022 - 10/2014
3Chemokine ReceptorsIBA
10/2014 - 10/2013
2Adenosine A3 ReceptorIBA
03/2022 - 01/2019
2Anti-Inflammatory Agents (Anti-Inflammatories)IBA
03/2022 - 01/2022
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
03/2022 - 01/2022
2Adenosine (Adenocard)FDA LinkGeneric
08/2020 - 01/2018
2Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2018
1AutoantibodiesIBA
02/2022
1Polysaccharides (Glycans)IBA
02/2022
1Glutamic Acid (Glutamate)FDA Link
01/2022
1Excitatory Amino AcidsIBA
01/2022
1Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2022
1Purinergic P2X7 ReceptorsIBA
12/2021
1Purinergic Receptors (Receptors, Purine)IBA
12/2021
1Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA
10/2021
1capadenosonIBA
10/2020
1Adenosine A2B ReceptorIBA
08/2020
1NucleosidesIBA
01/2020
1Potassium Channels (Potassium Channel)IBA
01/2020
1dofetilide (Tikosyn)FDA Link
10/2019
1LUF7244IBA
10/2019
1Nonesterified Fatty Acids (NEFA)IBA
01/2019
1CB2 Cannabinoid ReceptorIBA
02/2018
1Dronabinol (THC)FDA LinkGeneric
01/2018
1CannabinoidsIBA
01/2018
1Apolipoproteins E (ApoE)IBA
01/2017
1sertindole (Serdolect)IBA
04/2016
1AstemizoleIBA
04/2016
1CC ChemokinesIBA
07/2015
1CCR5 Receptors (CCR5 Receptor)IBA
02/2015
1Ether (Diethyl Ether)IBA
01/2014
1Luteinizing Hormone (Lutropin)FDA LinkGeneric
04/2009
1LH Receptors (LH Receptor)IBA
04/2009

Therapy/Procedure

2Precision Medicine
06/2022 - 01/2022
1Therapeutics
11/2021